The science of cannabis - including hemp - is still in its infancy, and while everyone at Forge is working diligently to bridge the gaps in our understanding of this incredible plant, there is still much to discover.
The word 'cannabinoid' refers to all chemical substances found in the cannabis plant that interact with out Endocannabinoid System (ECS). Research has found that the cannabis plant is generally capable of producing between 80 and 100 different cannabinoids (of which CBD is one).
In recent years cannabis/CBD research has entered a 'Renaissance Era,' and we're starting to discover the wonders of other less-known cannabinoids like cannabigerol (CBG) and cannabinol (CBN).
One thing we believe in: Cannabinoids work best when they work together!
In our opinion, CBD works best when it still contains traces of alternate cannabinoids. This theory is what makes whole plant extracts superior to pure CBD isolates. Although each cannabinoid may work wonders on its own when independently isolated, both our research and customer feedback have shown that results improve dramatically when cannabinoids are taken together and allowed to mix as nature intended.
Cannabigerol (CBG) is relatively new to the public eye. This intriguing cannabinoid is a know as a "precursor." It normally converts naturally into CBD or THC as the plant reaches maturity, which leaves a low percentage (often less than 1%) of CBG in the biological flower. Recently, however, plant breeders have fostered genetic strains that maintain those high levels of CBG throughout the plant's life.
So far, studies have shown some positive indications that CBG may help with colitis, neurodegeneration, and even cancer.
"CBG is the precursor to CBD, CBC, and THC," says Dr. Fokialakis, Chief Scientific Officer at Folsom & Forge. "It's sometimes referred to as the "stem cell" of the cannabis plant."
What does this mean? "CBGA (the acidic, inactive form of CBG) changes, is broken down, and becomes the base molecule that other cannabinoids then form from," which would include other natural cannabinoids such as CBD.
COMBINING CANNABINOIDS: THE ENTOURAGE EFFECT
The "Entourage Effect" theory gained ground in 2011 when a study published in the British Journal of Pharmacology reviewed the potential interactions between THC and various cannabinoids and terpenes. For example, the study suggested alpha pinene—a terpene that gives some plant varieties a fresh pine-like scent—might help preserve a molecule called acetylcholine, which has been implicated in memory formation. “So one main side effect of THC is short-term memory impairment,” the study says. “People go, ‘Uh…what were you saying?’ That can be prevented if there’s pinene in the cannabis.”
At Forge we're investing in pushing the boundaries of how humans interact with all cannabinoids, not only CBD. That's why our initial line of products contains a proprietary formulation of CBD, CBG and selected terpenes for authentic flavor.
After years of study, and trial and error, we're excited to finally launch what we consider to be ultra-premium CBD products, made in our cGMP certified facility and now available worldwide.